Endocrine-Disrupting Chemicals: Possible Genesis of Ovarian Tumors

Background: Prolonged exposure to environmental toxicants like endocrine-disrupting chemicals has been linked several ovarian pathologies. Exposure may start at any time of life from the fetal stage adulthood resulting in various health complications The purpose our study is compare concentration levels and association benzopyrene, bisphenol A genistein patients with tumors normal control group. We also sort evaluate predictive performance tumors. Methods: case-control was conducted for randomly selected participants involving 30 controls. radiologically diagnosed histopathological confirmed were included between January 2022 December 2022. Urine samples each group analyzed using liquid chromatography-mass spectrometry. Descriptive analysis normally distributed continuous variables done accordingly. Concentration assessed Mann-Whitney test. pathological binary logistic regression. Evaluation diagnostic ROC curve. Results: Overall, significantly (P = 0.000) older than healthy Mean years (SD) 36.7 (7.90) 28.8 (4.89) women respectively. Endometriomas had highest incidence 50%. level benzopyrene higher those group, while Benzopyrene associated cysts, cysts positively correlated these EDCs, OR value 64.79 0.005) 9.609 0.001) A. Genistein negatively tumors, 0.153 0.007). Diagnostic on AUC genistein</